USA Today

Saquon Barkley likely out Week 6 with low-ankle sprain

New York Giants’ running back Saquon Barkley will likely miss Week 6 and possibly more with a low-ankle sprain suffered Week 5 vs Dallas Cowboys (per Ian Rapoport)

Fantasy Impact: Big blow for Barkley and Barkley managers as the running back was just starting to look right post ACL injury. With Barkley out Sunday, Devontae Booker was the Giants’ No. 1 back. He had 19 touches and scored 2 touchdowns vs the Cowboys. Booker has RB2 value with Barkley out for Week 6. The Giants take on the Los Angeles Rams next week.