With all of the teams in the NFL playing either eight or nine games thus far, it might be a perfect time for a refresher on how to put together lineups and what contests to play in NFL DFS on DraftKings. For those that need a refresher, I wrote articles on ideal roster construction and contest selection on DraftKings before the regular season began.
Every week is different in the NFL, so there are certainly exceptions you can make like single-stacking certain quarterbacks. There are also certain situations where you don’t need to use a bring-back player from the opposing team you stack.
After getting a chance to look at how to construct lineups and what lineups you should enter in hopes to maximize your return on investment, here are my favorite stacks for the Week 10 main slate on DraftKings.
Related: NFL DFS Picks for Week 10 DraftKings Main Slate
Patrick Mahomes ($7,900) + Travis Kelce ($7,800) or JuJu Smith-Schuster ($6,000)
Mahomes is averaging 27.7 points per game on DraftKings after recording a season-high 38.1 points in Week 9 vs the Titans. While the Chiefs are spreading the ball around more with Tyreek Hill no longer on the roster, Kelce and Smith-Schuster are the two primary targets.
Kelce boasts a 23.1% target share in Kansas City’s passing game and Smith-Schuster has posted 18-plus points in three straight games. I like Mecole Hardman if he’s active on Sunday, but if he’s ruled out, I’m fine using Kadarius Toney and Marquez Valdes-Scantling in stacks with Mahomes.
Bring-back options: Travis Etienne Jr. ($7,100), Christian Kirk ($5,900), Zay Jones ($4,400), Evan Engram ($3,300)
Etienne has immediately become a bell-cow running back since the departure of James Robinson as he’s garnered 27-plus touches in his first two starts. Kirk is the No. 1 target for Trevor Lawrence and he’s priced under $6,000 on DraftKings in a game where the Jaguars could be playing from behind. Jones and Engram have been inconsistent every week, but they’re fine salary-relief options in a game with the highest projected total (50.5) on the main slate.
Tua Tagovailoa ($6,700) + Tyreek Hill ($9,100) or Jaylen Waddle ($7,600)
When the Dolphins have Tagovailoa under center, they look like one of the best offenses in the NFL. The trio of Tagovailoa, Hill, and Waddle has been lethal this season and Miami has the second-highest projected team total (26.5) on the main slate.
Hill and Waddle have a combined 52.8% target share, so more than half of the passing volume is going in their direction. It’s hard to fit Hill and Waddle in the same lineup, so you can pivot to Mike Gesicki or even stack Tagovailoa with Jeff Wilson Jr. after he caught three passes for 21 yards and a touchdown in his debut with the Dolphins in Week 9.
Bring-back options: Nick Chubb ($8,100), Amari Cooper ($6,500), Donovan Peoples-Jones ($4,300)
Chubb is one of the best running backs in the NFL and he’s produced 20-plus points on DraftKings in five games this season. The Browns don’t throw the ball 50-plus times with Jacoby Brissett at the helm, but Cooper and Peoples-Jones could be busy this week with David Njoku not practicing. In the first eight games of the season, Cooper has a modest 25.8% target share for the Browns.
Trevor Lawrence ($5,400) + Christian Kirk ($5,900) + Zay Jones ($4,400) or Evan Engram ($3,300)
While I like the Chiefs a lot this week, I also like the Jaguars in the same game. Lawrence has shown improvements this season and with Etienne likely being one of the highest-rostered running backs in Week 10, using Jacksonville’s aerial attack could differentiate from those that use Etienne.
Kirk is the primary wideout to target in the offense as he’s shown a decent ceiling this season despite his lack of consistent production in recent weeks. Engram is questionable to suit up on Sunday, so make sure to keep tabs on his status before using him in your lineups. Dan Arnold would likely start at tight end if Engram is unable to go on Sunday.
Bring-back options: Travis Kelce ($7,800), JuJu Smith-Schuster ($6,000), Kadarius Toney ($5,000), Mecole Hardman ($4,500)
Spending up at the tight end position can be contrarian in tournaments and it typically pays off to pay up for Kelce. Kelce is averaging 22.1 PPG on DraftKings (most among TEs on the main slate) and the second-highest scorer is T.J. Hockenson at 13.1 PPG. If Hardman is inactive this week, Smith-Schuster, Toney, and Valdes-Scantling are viable bring-back options for Jaguars stacks.
Justin Fields ($6,500) + Darnell Mooney ($5,500) + Chase Claypool ($4,800) or Cole Kmet ($3,400)
It’s certainly risky trying to double-stack the Bears due to the lack of passing volume Fields typically has, so I’m fine single-stacking him. Mooney leads the Bears with a 27.7% target share as he’s seen no fewer than five targets since Week 2.
Claypool is entering his second game with Chicago, so he could see an expanded workload in Week 10 against a Detroit defense that is allowing the fourth-most points per game to WRs this season. Kmet has hauled in three touchdowns in the last two games and he saw a season-high six targets in Week 9.
Bring-back options: Amon-Ra St. Brown ($6,900), D’Andre Swift ($6,400), Kalif Raymond ($4,400)
St. Brown had a stellar start to the season with 62.8 combined points on DraftKings in the first two weeks. However, he’s yet to score 14-plus points since Week 2, though, he’s gotten nine-plus targets in each of the last two games. Swift has seen his role reduced as he gets eased back into the offense due to an injury, so if it’s announced that he won’t get his normal workload, Jamaal Williams could become a better play. Raymond is a fine salary-relief option, especially if Josh Reynolds is inactive again.
Derek Carr ($5,600) + Davante Adams ($8,700) + Mack Hollins ($4,200) or Foster Moreau ($3,200)
Someone might be asking if something is wrong in my life because I’m recommending the Raiders this week. Everything is perfectly fine at home, but it feels like if the Raiders are going to show much of anything on offense, it would be this week.
The Colts named Jeff Saturday their interim head coach after firing Frank Reich despite him not having any coaching experience in the NFL. With the Raiders placing Darren Waller and Hunter Renfrow on injured reserve, it makes it easier to stack Las Vegas this week. Adams and Hollins are the primary targets, but I’m fine using Josh Jacobs in Raiders stacks due to the lack of options Carr now has.
Bring-back options: Jonathan Taylor ($7,500), Michael Pittman Jr. ($6,200), Alec Pierce ($4,100), Parris Campbell ($3,900)
At the moment, it appears there’s a chance that Taylor starts for the Colts on Sunday, making him a potential value at $7,500 against a Raiders defense that is giving up the fifth-most points per game to RBs. Deon Jackson is also dealing with an injury, so it remains to be seen what the Colts’ backfield looks like on Sunday. It’s hard to trust the wide receivers on the Colts while Sam Ehlinger is at quarterback, but Pittman has received at least eight targets in four of the last five games.